Dec 2024 Congrats to Trey for receiving an American Heart Association fellowship!

Nov 2024 Paige and Sasha presented posters at a Vanderbilt Undergraduate poster session!

Oct 2024 Welcome Sophie (graduate student) for a rotation in the lab!

Sept 2024 Welcome Kayla (graduate student) for a rotation in the lab!

Sept 2024 Matt’s paper “ParSE-seq: a calibrated multiplexed assay to facilitate the clinical classification of putative splice-altering variants” is out at Nature Communications! Link

Sept 2024 Lab ping pong tournament!

August 2024 Welcome back Sophie! Sophie worked in the lab for 3 years as an undergraduate and now returned as a research assistant.

August 2024 Ayesha gave a Variant Effects Seminar on high-throughput studies of potassium channel genes.

August 2024 Sasha presented to the MARC program on her summer research.

August 2024 Welcome Peyton (graduate student) for a rotation in the lab!

July 2024 Our paper validating an SCN5A automated patch clamp assay is now published in Circulation: Genomic and Precision Medicine. Link

July 2024 Welcome Jessa (postdoc) to the lab!

June 2024 Welcome Rosy (undergraduate) for the summer!

June 2024 We were happy to host our “Cardiovar” collaborators for a 2 day meeting in Nashville!

May 2024 Our comprehensive scan of KCNE1 variants is now published in Genome Medicine. Link

May 2024 Welcome to Rosy (undergraduate) for a summer stint in the lab! In her first week Rosy has already cloned two plasmids!

April 2024 Our paper “Minimum information and guidelines for reporting a Multiplexed Assay of Variant Effect” is out at Genome Biology! Link

April 2024 A week of transitions: We are sad to say goodbye to Zerubabell who is off to Harvard Medical School. But excited to welcome Ellen and Trey (PhD students) to the lab!

April 2024 Our paper “Minimum information and guidelines for reporting a multiplexed assay of variant effect” has been published at Genome Biology. Pubmed

March 2024 Ryder presented his undergraduate research at a Vanderbilt poster session.

Feb 2024 Congrats to Sasha for being named a Maximizing Access to Research Careers (MARC) undergraduate scholar! This is a competitive pre-PhD program at Vanderbilt.

Jan 2024 Andrew attended the Worldwide Sodium Channel meeting in Grindelwald, Switzerland.

Jan 2024 Check out our preprint “Multi-site validation of a functional assay to adjudicate SCN5A Brugada Syndrome-associated variants.”

Jan 2024 Welcome Trey (graduate student) for a rotation in the lab.

Nov 2023 Welcome Megan and Ellen (graduate students) for a rotation in the lab.

Nov 2023 Congrats to Matt for winning the Genetics and Precision Medicine Early Career Investigator competition at the American Heart Association meeting for his work on high-throughput splicing assays! Read the preprint here.

Sept 2023 Lots of new faces in the lab! Welcome to Zerubabell (Research Assistant), Marylssa (Undergrad) and Sasha (Undergrad)!

August 2023 It was great having Renaya in the lab as a visiting summer student. Renaya made and studied 10 variants by automated patch clamping and made a CRISPR mutant line...I wish I had been as productive as her when I was starting off in research! -Andrew

July 2023 Thrilled to receive a R35 MIRA grant from the NIH! This 5-year grant will help fund our research on ion channel variants.

May 2023 Our new preprint—a comprehensive study of 2,500 variants in KCNE1! Link

May 2023 Congrats to Matt for defending his thesis! We had a lot of fun designing the cake…

March 2023 Welcome to Megan (graduate student) for a rotation in the lab!

February 2023 Welcome to James (graduate student) for a rotation in the lab!

January 2023 Our CardioVar collaborative group (teams from Vanderbilt, Stanford, U. Toronto, and Harvard) met for an all-day retreat in Stanford! Lots of great discussions/plans for high-throughput cardiac genetics.

November 2022 Check out Andrew’s review “Genetics of congenital arrhythmia syndromes: the challenge of variant interpretation.” Link

October 2022 Ayesha gave a talk at the American Society for Human Genetics meeting in LA on deep mutational scanning of potassium channel genes.

October 2022 Matt’s paper characterizing splice-disrupting variants in arrhythmia genes was published in Circulation: Genomics and Precision Medicine! Link

August 2022 Welcome Jeremy (RA) and Paige (undergrad) to the lab!

August 2022 Zerubabell and Genevieve presented posters on their summer research projects. Combined they cloned 109 successful plasmids!

August 2022 Congrats to Matt for passing his qualifying exam!

June 2022 Welcome summer students Zerubabell and Genevieve to the lab!

June 2022 Congrats to Ayesha and Matt for their awards for best presentations at the Genetics Interest Group seminars and Matt for his talk at the Vanderbilt Genetics Institute retreat!

May 2022 Our arrhythmia sequencing study was featured in the VUMC Reporter.

April 2022 Welcome Kara to the lab and farewell to Ashli as she heads off to medical school!

April 2022 The lab has transitioned from a K99 to an R00 grant!

March 2022 Check out our preprint on candidate splicing variants

March 2022 Our study of dominant negative SCN5A variants is out in Genetics in Medicine! Link

March 2022 Congrats Ayesha on her thesis defense!

March 2022 Welcome Maria to the lab!

Feb 2022 Welcome Adi and Sophie to the lab!

Jan 2022 Check out a 10 minute talk Andrew gave on our research. Youtube

Dec 2021 Our study of arrhythmia variants in >20,000 individuals in the eMERGE-seq cohort has been accepted at Circulation! Link

Nov 2021 Matthew gave a talk at the American Heart Association Scientific Sessions.

Nov 2021 Andrew gave a talk and Ayesha gave a poster at the Vanderbilt Translational Research Forum.

Oct 2021 Our first lab preprint (on SCN5A dominant negative effects) has been posted. Looking forward to the first lab paper!

Sept 2021 Ashli has joined the lab as a Research Technician!

July 2021 The Glazer lab has officially opened!

June 2020 We had our first in-person meeting of VanCART (Vanderbilt Center for Arrhythmia Research and Therapeutics) in over a year!

May 2021 Andrew co-led an American Journal of Human Genetics webinar on the use of functional studies in variant classification.

June 2020 Our work on high-throughput arrhythmia variant reclassification was featured in VUMC Reporter and VUMC Discover.

The Glazer lab is also somewhat active on Twitter: @amglazer